No new HIV infections have
occurred among more than 500 users of the Kaiser Permanente healthcare provider
system in the US in members using pre-exposure prophylaxis — better known as
PrEP.
However, condom use appears to be
declining among a subset of gay men, according to a small survey presented at a
December 1 forum commemorating

A modelling study based on the UK’s HIV epidemic among gay
men estimates that two-thirds of infections originate in men with undiagnosed
HIV, 85% in men who are not taking treatment and 90% within the context of an
ongoing sexual partnership. Moreover, HIV transmissions most frequently involve
men under the age of 35 who

Difficult-to-treat hepatitis C patients with
liver cirrhosis who were not cured with a prior course of first-generation HCV
protease inhibitors had a sustained response rate of 96-97% when re-treated
with sofosbuvir/ledipasvir with ribavirin for 12 weeks or without ribavirin for
24 weeks, researchers reported at the
American Association for the Study of Liver
Diseases (AASLD) Liver

Poor weight gain
after starting antiretroviral therapy (ART) is associated with increased
mortality risk for children with HIV, investigators report in the online
edition of AIDS. An international
team of researchers developed a model to examine the association between weight
gain and mortality risk for children starting ART. Poor weight gain was
associated with increased mortality

HIV infection is
associated with reduced physical performance, investigators report in the
online edition of AIDS. They also
found that people living with HIV who had reduced physical function had a
significant increase in their mortality risk.
The study population
comprised middle-aged HIV-positive and HIV-negative people in Baltimore, United States, who either currently inject drugs or

Numerosi i temi affrontati.Tra i principali: Comorbosità, ICAAC, Glasgow, EACS a Roma, Epatite C: nuovi farmaci e attivismo, Nuove sfide in Sanità. Ringraziamo Antonella Cingolani, Marco Borderi, Gioacchino Angarano, Giulio Maria Corbelli per i preziosi contributi.

Harm reduction interventions often fail to engage people who
inject drugs because they over-emphasise infection and risk, Magdalena Harris
of the London School of Hygiene and Tropical Medicine told the recent HIT Hot
Topics conference in Liverpool. Her interviewees frequently adopted safer
injecting practices, but were more motivated by a desire to have a

Harm reduction interventions often fail to engage people who
inject drugs because they over-emphasise infection and risk, Magdalena Harris
of the London School of Hygiene and Tropical Medicine told the recent HIT Hot
Topics conference in Liverpool. Her interviewees frequently adopted safer
injecting practices, but were more motivated by a desire to have a

An interferon-free
regimen of sofosbuvir plus ledipasvir (Harvoni)
taken with ribavirin for 12 or 24 weeks led to sustained virological response
in nearly all HCV genotype 1patients
with fibrosis or less-advanced liver cirrhosis, researchers reported at the American
Association for the Study of Liver Diseases (AASLD) Liver Meeting last month in
Boston, United States. Response rates

Regimens containing sofosbuvir
(Sovaldi) – including sofosbuvir plus
simeprevir (Olysio) – work well for people
with hepatitis C genotype 1 in real-world use, which to date has included some
of the patients most urgently in need of treatment at the dawn of the
interferon-free era, according to a pair of presentations at the American
Association for